what causes gouty arthritis - Uric Acid Testing
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Uric Acid Testing
Definition Uric acid tests are tests that are done to measure the levels of uric acid in blood serum or in urine. Purpose
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Normal results Blood test Reference values for blood uric acid vary from laboratory to laboratory but are generally found within the following range: Male: 2.1-8.5 mg/dL; female: 2.0-6.6 mg/dL. Values may be slightly higher in the elderly.
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Uric acid is a waste product that results from the breakdown of purine, a nucleic acid. (Nucleic acids are the building blocks of DNA.) Uric acid is made in the liver and excreted by the kidneys. If the liver produces too much uric acid or the kidneys excrete too little, the patient will have too much uric acid in the blood. This condition is called hyperuricemia. Supersaturated uric acid in the urine (uricosuria) can crystallize to form kidney stones that may block the tubes that lead from the kidneys to the bladder (the ureters). As you progress deeper and deeper into this composition on what causes gouty arthritis, you are sure to unearth more information on what causes gouty arthritis. The information becomes more interesting as the deeper you venture into the composition.
Preparation The uric acid test requires either a blood or urine sample. For the blood sample, the patient should be fasting (nothing to eat or drink) for at least eight hours before the test. The urine test for uric acid requires a 24-hour urine collection. The urine test does not require the patient to fast or cut down on fluids. Some laboratories encourage patients to drink plenty of fluids during the collection period. We do hope that you find the information here something worth recommending others to read and think about once you complete reading all there is about what causes gouty arthritis.
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The laboratory should also be notified if the patient has had recent x-ray tests requiring contrast dyes. These chemicals increase uric acid levels in urine and decrease them in blood. It is only if you find some usage for the matter described here on what causes gouty arthritis that we will feel the efforts put in writing on what causes gouty arthritis fruitful. So make good usage of it!
Precautions Blood test Patients scheduled for a blood test for uric acid should be checked for the following medications: loop diuretics (Diamox, Bumex, Edecrin, or Lasix); ethambutol (Myambutol); vincristine (Oncovin); pyrazinamide (Tebrazid); thiazide diuretics (Naturetin, Hydrex, Diuril, Esidrix, HydroDiuril, Aquatensen, Renese, Diurese); aspirin (low doses); acetaminophen (Tylenol); ascorbic acid (vitamin C preparations); levodopa (Larodopa); or phenacetin. These drugs can affect test results. Saying that all that is written here is all there is on what causes gouty arthritis would be an understatement. Very much more has to be learnt and propagated bout what causes gouty arthritis.
Abnormally low uric acid levels may indicate that the patient is taking allopurinol or probenecid for treatment of gout; may be pregnant; or suffers from Wilson's disease or Fanconi's syndrome.
Certain foods that are high in purine may increase the patient's levels of uric acid. These include kidneys, liver, sweetbreads, sardines, anchovies, and meat extracts. Looking for something logical on what causes gouty arthritis, we stumbled on the information provided here. Look out for anything illogical here.
Description The uric acid blood test is performed on a sample of the patient's blood, withdrawn from a vein into a vacuum tube. The procedure, which is called a venipuncture, takes about five minutes. The urine test requires the patient to collect all urine voided over a 24-hour period, with the exception of the very first specimen. The patient keeps the specimen container on ice or in the refrigerator during the collection period.
Key Terms - Fanconi's syndrome
- A rare disorder caused by vitamin D deficiency or exposure to heavy metals.
- Gout
- A metabolic disorder characterized by sudden recurring attacks of arthritis caused by deposits of crystals that build up in the joints due to abnormally high uric acid blood levels. In gout, uric acid may be overproduced, underexcreted, or both.
- Hyperuricemia
- Excessively high levels of uric acid in the blood, often producing gout.
- Purine
- A white crystalline substance that is one of the building blocks of DNA. Uric acid is produced when purine is broken down in the body.
- Uric acid
- A compound resulting from the body's breakdown of purine. It is normally present in human urine only in small amounts.
- Uricosuria
- Increased levels of uric acid in the urine.
- Wilson's disease
- A rare hereditary disease marked by the buildup of copper in the liver and brain, causing loss of kidney function.
Further Reading For Your Information Books - Laboratory Test Handbook, edited by David S. Jacobs. Cleveland, OH: Lexi-Comp Inc., 1996.
- Mosby's Diagnostic and Laboratory Test Reference, edited by Kathleen Deska Pagana and Timothy James Pagana. St. Louis: Mosby-Year Book, Inc., 1998.
- Springhouse Corporation. Handbook of Diagnostic Tests, edited by Matthew Cahill. Springhouse, PA: Springhouse Corporation, 1995.
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Urine test Reference values for 24-hour urinary uric acid vary from laboratory to laboratory but are generally found within the following range: 250-750 mg/24 hours. We hope you develop a better understanding of what causes gouty arthritis on completion of this article on what causes gouty arthritis. Only if the article is understood is it's benefit reached.
Increased production of uric acid may result from eating foods that are high in purine. Increased uric acid levels due to overproduction may also be caused by gout, by a genetic disorder of purine metabolism, or by metastatic cancer, destruction of red blood cells, leukemia, or cancer chemotherapy.
Decreased excretion of uric acid is seen in chronic kidney disease, low thyroid, toxemia of pregnancy, and alcoholism. Patients with gout excrete less than half the uric acid in their blood as other persons. Only 10-15% of the total cases of hyperuricemia, however, are caused by gout.
Urine test Patients should be checked for the following medications before the urine test: diuretics, aspirin, pyrazinamide (Tebrazid), phenylbutazone, probenecid (Benemid), and allopurinol (Lopurin). If the patient needs to continue taking these medications, the laboratory should be notified.
Risks Risks for the blood test are minimal, but may include slight bleeding from the puncture site, a small bruise or swelling in the area, or fainting or feeling lightheaded. So after reading what we have mentioned here on what causes gouty arthritis, it is up to you to provide your verdict as to what exactly it is that you find fascinating here.
The Internet Guide: Gout - http://gout.smartadsscrets.com The Internet Guide: Purines - http://gout.smartadssecrets.com/purines Writing on what causes gouty arthritis proved to be a gamble to us. This is because there simply seemed to be nothing to write about in the beginning of writing. It was only in the process of writing did we get more and more to write on what causes gouty arthritis.
The uric acid tests are used to evaluate the blood levels of uric acid for gout and to assess uric acid levels in the urine for kidney stone formation. The urine test is used most often to monitor patients already diagnosed with kidney stones, but it can also be used to detect disorders that affect the body's production of uric acid and to help measure the level of kidney functioning.
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